The man suspected in the disappearance of Natalee Holloway has hinted that he might confess to the murder of a young woman in Peru. He's on trial there now, apparently considering a plea in that case. Dr Drew and his guests wonder what he's up to and if this is the start of his coming clean about Natalee.

Plus, "real housewife" Kyle Richard tells Dr. Drew why you're seeing another side to her on this season's shows. Just which one is the true Kyle?

And Dr. Drew will introduce us to a young man who is going blind from an inherited disease. He's running a marathon to raise money for the cause, before his sight finally leaves him.

Watch Dr. Drew tonight and every weeknight at 9 on HLN.

A new video has surfaced online of Casey Anthony. HLN's Dr. Drew and his guests take a closer look.